Dr. Avraham Ashkenazi
Dr. Ashkenazi is a new faculty member at Tel Aviv University’s Faculty of Medicine and School of Neuroscience. He returned to Israel from a postdoc at the Cambridge Institute for Medical Research. His research utilizes state-of-the-art technologies to elucidate cellular mechanisms of neurological disorders. Some of these diseases progress late in life, such as Huntington's Parkinson's disease. A common characteristic in these diseases is the accumulation of proteins that are not folded properly and can form aggregates in the brain, which could lead to neuron death. Dr. Ashkenazi’s lab is currently focused on the ubiquitin-proteasome and autophagy pathways, the main routes to break down aggregate-prone proteins. He aims to elucidate novel regulatory pathways of protein homeostasis to better understand the basis of and treat these devastating diseases.